選單
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學術諮詢委員 研究人員 研究人員 合聘研究人員 兼任研究人員 Emeriti Faculty 行政技術人員
本所研究 近期活動
語言

王玉麟

特聘研究員

王玉麟
Email: ylwang[at]pub.iams.sinica.edu.tw
Office: R303
Tel: +886-2-2366-8233
Lab: NB01 & NB02
Lab Tel: +886-2-2366-8241
Surface Nanostructure Lab

研究興趣

  • Physics and chemistry of nanostructures, application of nanotechnology to biomedical sciences, focused ion beam (FIB) technology, and surface enhanced Raman spectroscopy (SERS).

研究概述

王玉麟博士研究特殊奈米結構，以及探索其用於增強表面拉曼光譜信號，並開發出有序的金屬奈米粒子陣列，且發現其上的電漿子可用來增強細菌的拉曼光譜信號。此發現在生醫應用上具有潛力。目前正與醫療團隊合作測試其可行性。王博士與魏金明博士團隊，在原子與分子之表面魔術數團簇（Surface Magic-Number Clusters, SMCs）的自組織研究上，曾有重要突破。此研究在表面上精確構建奈米結構對於奈米科學和奈米技術至關重要。SMC是在特定晶體表面的特定尺寸下形成的穩定原子或分子結構，能夠實現原子級精度的奈米結構陣列。王博士團隊在矽（111）上發現了第一個10個鎵原子組成的SMC，在矽（111）上創建了第一個二維SMC晶格，並與俄羅斯實驗學家合作，觀察到第一個C60分子在金-銦（111）上的分子SMC。這些發現揭示了基本的自組織機制，並為原子級精度的奈米尺度設計開闢了新的途徑。此外王玉麟博士與王俊凱博士的合作研究團隊，發現基於陽極氧化鋁（AAO）奈米通道中銀奈米粒子的均勻「電漿熱點」陣列，可用於表面增強拉曼光譜（Surface-Enhanced Raman Spectroscopy, SERS）。自組織陽極氧化鋁（Anodic Aluminum Oxide, AAO）模板為奈米粒子及奈米線生長提供了一個多功能的平台，能夠讓相鄰的銀奈米粒子之間形成即為靠近且均勻的「電漿熱點」，而顯著提高表面增強拉曼光譜的靈敏度、均勻性和穩定性。這一系列的研究有助於將SERS確立為一種可靠的分析工具，實現如敗血症患者抗生素敏感性測試等應用。

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學歷

  • 民國68年，台灣大學物理系學士
  • 民國77年，美國芝加哥大學物理博士

經歷

  • ​貝爾實驗室博士後研究員(1989-1991)
  • 原分所副研究員(1991-1998)
  • 原分所研究員(1998-2010)
  • 台灣大學物理系合聘教授(1999-2021)
  • 國科會自然處物理學門召集人(2000-2001)
  • 原分所副所長(2001-2004)
  • 國科會自然處物理學門諮議委員(2002-2005)
  • 原分所所長(2004-2010)
  • Journal of Physical Chemistry, USA國際諮詢委員(2007-2009)
  • 原分所特聘研究員(2011-迄今)
  • 中央研究院應用科學研究中心學術諮詢委員(2013-2016)
  • 國科會「卓越領航計畫計畫」主持人(2013-2017)
  • 科技部「奈米科技前瞻應用主軸計畫」共同召集人(2014-2017)
  • 科技部「學術攻頂研究計畫」主持人(2017-2022)
  • 中央研究院「材料與分析科技探索計畫」總召集人(2017-迄今)
  • 國科會「卓越領航計畫計畫」主持人(2022-迄今)

獎項與榮譽

  • 民國81年，國科會優等獎
  • 民國91年，第一屆有庠科技論文獎(奈米科技)
  • 民國94年至99年，傑出人才獎座
  • 民國98年，第七屆有庠科技講座(奈米科技)
  • 民國98年，行政院傑出科技貢獻獎
  • 民國99年，第六屆奈米產業科技菁英獎
  • 民國99年，中華民國物理學會會士
  • 民國100年，美國物理學會會士
  • 民國103年， 科技部傑出研究獎
  • 民國106年，教育部學術獎
  • 民國107年，中華民國化學會化學學術獎章
代表著作
  1. “Scanning Ion Microscopy: Elemental Maps at High Lateral Resolution”, R. Levi-Setti, Y. L. Wang, and G. Crow, Invited paper, Pittsburgh Conf. on Analytical Chemistry and Applied Spectroscopy, February 1985, Appl. Surf. Sci. 26, 249-264 (1986).
  2. “Imaging SIMS at 20 nm Lateral Resolution: Exploratory Research Applications”, R. Levi-Setti, G. Crow, and Y. L. Wang, Keynote paper, SIMS-V, Washington, D. C., September 1985, Secondary Ion Mass Spectrometry SIMS V, A. Benninghoven, R. J. Colton, D. S. Simons, and H. W. Werner, Eds., (Springer, Berlin 1986), 132-138.
  3. “Role of Native Oxide Layers in the Patterning of InP Using Focused Ion Beam and Ion Assisted Cl2 Etching”, Y. L. Wang, L. R. Harriott, R. A. Hamm, and H. Temkin, Appl. Phys. Lett. 56, 749-751 (1990).
  4. “Semiconductor Lasers Fabricated by Selective Area Epitaxy”, Y. L. Wang, H. Temkin, R. A. Hamm, R. D. Yadvish, D. Ritter, L. H. Harriott, and M. B. Panish, Electronic Letters 27, 1324-1326 (1991).
  5. “Design Principles of an Optimized Focused Ion Beam System”, Y. L. Wang and Z. Shao, a chapter in "Advances in Electronics and Electron Physics," P. W. Hawkes Ed., Vol. 81, 177-210 (Academic Press, Boston, 1991).
  6. “Direct Observation of Two Dimensional Magic Clusters”, M. Y. Lai and Y. L. Wang, Phys. Rev. Lett. 81, 164-167 (1998).
  7. “Growth of Ga-Induced Nanostructures on Si(111): from Magic Clusters to Inconmmensurate Structure”, M. Y. Lai and Y. L. Wang, Phys. Rev. B 60, 1764-1770 (1999).
  8. “Ordered Anodic Alumina Nano-channels on Focused-Ion-beamPrepatterned Aluminum Surfaces”, C. Y. Liu, A. Datta, and Y. L. Wang, App. Phys. Lett. 78, 120-122 (2001).
  9. “Self-Organized Two-Dimensional Lattice of Magic Clusters”, M. Y. Lai and Y. L. Wang, Phys. Rev. B64, 241404(R)-241404-4 (2001).
  10. “Structure Determination of Surface Magic-Clusters”, H. H. Chang,M. Y. Lai, J. H. Wei, C. M. Wei, and Y. L. Wang, Phys. Rev. Lett. 92, 066103 (2004).
  11. “Fabrication of Anodic Alumina Film with Custom-Designed Arrays of Nanochannels”, N. W. Liu, A. Datta, C. Y. Liu, C. Y. Peng, H. H. Wang, and Y. L. Wang, Advanced Materials 17, 222 (2005).
  12. “Highly Raman Enhancing Substrates Made of Ag-Nanoparticle Array with Tunable Sub-10 nm Gaps”, Huai-Hsien Wang, Chih-Yu Liu, Shr-Bin Wu, Nai-Wei Liu, Cheng-Yi. Peng, Tsu-Hsin Chan, Chen-Feng Hsu, Juen-Kai Wang, and Yuh-Lin Wang, Advanced Materials 18, 491-495 (2006).
  13. “Random and ordered arrays of surface magic clusters”, Y. L. Wang, A. A. Saranin, A. V. Zotov, M. Y. Lai, and H. H. Chang (Invited Review), International Reviews in Physical Chemistry 27, 317-360 (2008).
  14. “A High Speed Detection Platform Based on Surface-Enhanced Raman Scattering for Monitoring Antibiotic-Induced Chemical Changes in Bacteria Cell Wall”, Ting-Ting Liu, You-Hsuan Lin, Chia-Sui Hung, Tian-Jiun Liu, Yu Chen, Yung-Ching Huang, Tsung-Heng Tsai, Huai-Hsien Wang, Da-Wei Wang, Juen-Kai Wang, Yuh-Lin Wang, Chi-Hung Lin, PLoS ONE 4(5), e5470 (2009).
  15. “Broken Even/Odd Symmetry in Self-Selection of Distances between Nanoclusters due to Presence/Absence of Topological Solitons”, M. Y. Lai, J. P. Chou,O. A. Utas, N. V. Denisov, V. G. Kotlyar,D. Gruznev, A. Matetsky, A. V. Zotov, A. A. Saranin, C. M. Wei, Y. L. Wang, Phys. Rev. Lett. 106, 166101 (2011).
  16. “Funtionalized arrays of Raman-enhancing nanoparticles for capture and culture-free analysis of bacteria in human blood”, T. Y. Liu, K. T. Tsai, H. H. Wang, Y. Chen, Y. S. Chen, Y. C. Chao, H. H. Chang, C. H. Lin, J. K. Wang, Y. L. Wang, Nat. Commun. 2, 538 (2011).
  17. “Stepwise self-assembly of C60 mediated by atomic scale moiré magnifiers”, D.V. Gruznev, A.V. Matetskiy, L.V. Bondarenko, O.A. Utas, A.V. Zotov, A.A. Saranin,J.P. Chou, C.M. Wei, M.Y.Lai, and Y.L. Wang, Nat. Commun. 4, 1679 (2013).
  18. “Looking into Meta-Atoms of Plasmonic Nanowire Metamaterial”, Kun-Tong Tsai, Gregory A. Wurtz, Jen-You Chu, Tian-You Cheng, Huai-Hsien Wang, Alexey V. Krasavin, Jr-Hau He, Brian M. Wells, Viktor A. Podolskiy, Juen-Kai Wang, Yuh-Lin Wang, and Anatoly V. Zayats, Nano Lett. 14, 4971 (2014).
  19. “FePt Nanodendrites with High-Index Facets as Active Electrocatalysts for Oxygen Reduction Reaction”, D. Y. Wang, H. L. Chou, C. C. Cheng, Y. H. Wu, C. M. Tsai, H. Y. Lin, Y. L. Wang, B. J. Hwang, and C. C. Chen, Nano Energy 11, 631 (2015).
  20. “Highly Active and Stable Hybrid Catalyst of Cobalt-Doped FeS2 Nanosheets−Carbon Nanotubes for Hydrogen Evolution Reaction”, D. Y. Wang, M. Gong, H. L. Chou, C. J. Pan, H. A. Chen, Y. Wu, M. C. Lin, M. Guan, J. Yang, C. W. Chen, Y. L. Wang, B. J. Hwang, C. C. Chen, and H. Dai, J. Am. Chem. Soc. 137, 1587 (2015).
  21. “Quantification of biomolecules responsible for biomarkers in the surface-enhanced Raman spectra of bacteria using liquid chromatography-mass spectrometry”, Shirley W. Y. Chiu, H. W. Cheng, Z. X. Chen, H. H. Wang, M. Y. Lai, J. K. Wang and Y. L. Wang, Phys. Chem. Chem. Phys. 20, 8032 (2018).
  22. “Antibiotic Susceptibility Test with Surface-Enhanced Raman Scattering in a Microfluidic System”, K. W. Chang, H. W. Cheng, Jessie Shiue, J. K. Wang, Y. L. Wang, and N. T. Huang, Anal. Chem. 91, 10988 (2019).
  23. “Rapid antibiotic susceptibility testing of bacteria from patients' blood via assaying bacterial metabolic response with surface-enhanced Raman spectroscopy”, Y. Y. Han, Y. C. Lin, W. C. Cheng, Y. T. Lin, L. J. Teng, J. K. Wang, and Y. L. Wang, Scientific Reports, 10:12538 (2020).
  24. “Bacteria encapsulation and rapid antibiotic susceptibility test using a microfluidic microwell device integrating surface-enhanced Raman scattering”, H. K. Huang, H. W. Cheng, C. C. Liao, S. J. Lin, Y. Z. Chen, J. K. Wang, Y. L. Wang, and N. T. Huang, Lab on Chip, 20, 2520 (2020).
  25. “Sensible Functional Linear Discriminant Analysis Effectively Discriminates Enhanced Raman Spectra of Mycobacterium Species”, W. C. Cheng, L. H. Chen, C. R. Jiang, Y. M. Deng, D. W. Wang, C. H. Lin, R. W. Jou, J. K. Wang, and Y. L. Wang,  Analytical Chemistry 93, 2785 (2021).
  26. “Atomically-resolved interlayer charge ordering and its interplay with superconductivity in YBa2Cu3O6.81”, C. C. Hsu, B. C. Huang, Michael Schnedler, M. Y. Lai, Y. L. Wang, Rafal E. Dunin-Borkowski, C. S. Chang, T. K. Lee, Philipp Ebert and Y. P. Chiu, Nat. Comm. 12, 3839 (2021).
  27. “SERS‑based rapid susceptibility testing of commonly administered antibiotics on clinically important bacteria species directly from blood culture of bacteremia patients”, Y. Y. Han, J. T. Wang, W. C. Cheng, K. L. Chen, Y. Chi, L. J. Teng, J. K. Wang, and Y. L. Wang, World Journal of Microbiology and Biotechnology 39, 282 (2023).